BDBM50303574 (2,2,3,3-Tetrafluoro-1-methylcyclobutyl)(1-((tetrahydro-2Hpyran-4-yl)methyl)-1H-indol-3-yl)methanone::CHEMBL584528

SMILES CC1(CC(F)(F)C1(F)F)C(=O)c1cn(CC2CCOCC2)c2ccccc12

InChI Key InChIKey=ACLHVQFTZBYNIH-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303574   

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303574((2,2,3,3-Tetrafluoro-1-methylcyclobutyl)(1-((tetra...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303574((2,2,3,3-Tetrafluoro-1-methylcyclobutyl)(1-((tetra...)
Affinity DataEC50:  197nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303574((2,2,3,3-Tetrafluoro-1-methylcyclobutyl)(1-((tetra...)
Affinity DataKi:  1.45E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed