BDBM50307954 4-((4-Chlorobenzyloxy)methyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine::CHEMBL597793

SMILES NC1(COCc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=UFBYOZWKWYKBBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307954   

TargetRAC-alpha serine/threonine-protein kinase(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50307954(4-((4-Chlorobenzyloxy)methyl)-1-(7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of PKB in human U87MG cells assessed as GSK3-beta phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50307954(4-((4-Chlorobenzyloxy)methyl)-1-(7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PKBbeta by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed