BDBM50308613 2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one::CHEMBL592707

SMILES Cc1ccc(CN=Nc2nc(O)cs2)cc1

InChI Key InChIKey=ZUXHXVSJZRDQAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308613   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308613(2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)...)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308613(2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)...)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed