BDBM50313306 (1R,5S)-8-(4-tert-butylphenylsulfonyl)-3-ethoxy-8-azabicyclo[3.2.1]octane::CHEMBL1080886

SMILES CCOC1C[C@@H]2CC[C@H](C1)N2S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=OOTODNOGRPZZSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313306   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313306((1R,5S)-8-(4-tert-butylphenylsulfonyl)-3-ethoxy-8-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313306((1R,5S)-8-(4-tert-butylphenylsulfonyl)-3-ethoxy-8-...)
Affinity DataIC50: 114nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed