BDBM50313864 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(2,5-dimethyl-6-(pyrrolidin-1-yl)pyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL1085930

SMILES C[C@H](C1CC1)n1cc(Cl)nc(Nc2cc(C)c(nc2C)N2CCCC2)c1=O

InChI Key InChIKey=CWOHROWFYXLUGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313864   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313864((R)-5-chloro-1-(1-cyclopropylethyl)-3-(2,5-dimethy...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed