BDBM50314914 1'-(1H-indazole-7-carbonyl)-6,7-dimethylspiro[chroman-2,4'-piperidin]-4-one::CHEMBL1090120

SMILES Cc1cc2OC3(CCN(CC3)C(=O)c3cccc4cn[nH]c34)CC(=O)c2cc1C

InChI Key InChIKey=CHEUTPWOLURCHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314914   

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314914(1'-(1H-indazole-7-carbonyl)-6,7-dimethylspiro[chro...)
Affinity DataIC50: 163nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314914(1'-(1H-indazole-7-carbonyl)-6,7-dimethylspiro[chro...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed