BDBM50317779 CHEMBL1098491::diethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

SMILES CCOC(=O)C1C(C)=NC(C)=C(C(=O)OCC)C1(C)c1ccccc1

InChI Key InChIKey=HRKXPKCWTOLYLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317779   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317779(diethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyridi...)
Affinity DataIC50: 630nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317779(diethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyridi...)
Affinity DataIC50: 2.14E+3nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed