BDBM50317781 CHEMBL1096201::ethyl 5-acetyl-2,6-dimethyl-4-(naphthalen-2-yl)-1,4-dihydropyridine-3-carboxylate

SMILES CCOC(=O)C1=C(C)N=C(C)C(C1c1ccc2ccccc2c1)C(C)=O

InChI Key InChIKey=AXZLHNLDQQCYLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317781   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317781(ethyl 5-acetyl-2,6-dimethyl-4-(naphthalen-2-yl)-1,...)
Affinity DataIC50: 2.22E+3nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317781(ethyl 5-acetyl-2,6-dimethyl-4-(naphthalen-2-yl)-1,...)
Affinity DataIC50: 2.32E+3nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed