BDBM50317847 2-Benzoxy-5-(2-methylbenzo[d]thiazol-5-yl)benzonitrile::CHEMBL1098805

SMILES Cc1nc2cc(ccc2s1)-c1ccc(OCc2ccccc2)c(c1)C#N

InChI Key InChIKey=GGOPQZHINXTGIV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317847   

TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50317847(2-Benzoxy-5-(2-methylbenzo[d]thiazol-5-yl)benzonit...)
Affinity DataKi:  7.13E+3nMAssay Description:Displacement of [3HMPEP from rat cloned mGluR5 expressed in HEK293T cells by by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50317847(2-Benzoxy-5-(2-methylbenzo[d]thiazol-5-yl)benzonit...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs befor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed