BDBM50318995 2-((1-(3-(4-allyl-2-methoxyphenoxy)-2-hydroxypropyl)piperidin-4-yl)methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione::CHEMBL1084274

SMILES COc1cc(CC=C)ccc1OCC(O)CN1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1

InChI Key InChIKey=JNXQJQFGJQPMOR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318995   

TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318995(2-((1-(3-(4-allyl-2-methoxyphenoxy)-2-hydroxypropy...)
Affinity DataKi:  1.18E+3nMAssay Description:Antagonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318995(2-((1-(3-(4-allyl-2-methoxyphenoxy)-2-hydroxypropy...)
Affinity DataKi:  1.36E+3nMAssay Description:Antagonist activity at human adrenergic beta-1 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318995(2-((1-(3-(4-allyl-2-methoxyphenoxy)-2-hydroxypropy...)
Affinity DataKi:  3.29E+3nMAssay Description:Displacement of [125I]cyanopindolol from human adrenergic beta2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed