BDBM50322310 CHEMBL1170904::N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2R)-pyrrolidin-2-ylacetyl]amino}phenyl)pyridin-2-yl]furan-2-carboxamide

SMILES Oc1cc(F)ccc1-c1cc(-c2cccc(NC(=O)C[C@H]3CCCN3)c2)c(C#N)c(NC(=O)c2ccco2)n1

InChI Key InChIKey=RSYNYLIYCFUNTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322310   

TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2R...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2R...)
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed