BDBM50323405 1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)methyl)-4-(3-methoxyphenyl)piperazine::CHEMBL1209048

SMILES COc1cccc(c1)N1CCN(Cc2c(C)nn(c2C)-c2ccc(F)cc2)CC1

InChI Key InChIKey=STSDFTHBTSWXTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323405   

TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323405(1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-y...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323405(1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-y...)
Affinity DataIC50: 823nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed