BDBM50323835 CHEMBL1214341::N-(5-(trifluoromethyl)pyridin-2-yl)-7-(5-(trifluoromethyl)thiazol-4-yl)-1,8-naphthyridin-4-amine

SMILES FC(F)(F)c1scnc1-c1ccc2c(Nc3ccc(cn3)C(F)(F)F)ccnc2n1

InChI Key InChIKey=MPRGCUVQJWCKJG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323835   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50323835(N-(5-(trifluoromethyl)pyridin-2-yl)-7-(5-(trifluor...)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2011
Entry Details Article
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