BDBM50323964 1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide::CHEMBL1213934

SMILES Cc1c(cc(-c2ccccc2)n1C)C(=O)NCCCN1CCN(CC1)c1cccc2cccnc12

InChI Key InChIKey=HSGTXFOSGPTDRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323964   

TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323964(1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piper...)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323964(1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piper...)
Affinity DataIC50: 233nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323964(1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piper...)
Affinity DataIC50: 352nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed