BDBM50323978 CHEMBL1214302::N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2,4-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride

SMILES Cc1[nH]c(c(C)c1C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl)-c1ccccc1

InChI Key InChIKey=UPJDIJPBOJIDFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323978   

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323978(N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323978(N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323978(N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 162nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed