BDBM50323995 CHEMBL1214547::N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-(pyridin-4-yl)-1H-pyrrole-3-carboxamide

SMILES Cc1c(cc(-c2ccncc2)n1C)C(=O)NCCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=XOMXTKDEJJEEOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323995   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323995(N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 39nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323995(N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 85nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50323995(N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 175nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed