BDBM50324471 (E)-4-(4-oxo-2-styrylquinazolin-3(4H)-yl)benzoic acid::CHEMBL1214934

SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2)nc2ccccc2c1=O

InChI Key InChIKey=CLMUJDJFMCAVDV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324471   

TargetGlutamate receptor 1(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324471((E)-4-(4-oxo-2-styrylquinazolin-3(4H)-yl)benzoic a...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324471((E)-4-(4-oxo-2-styrylquinazolin-3(4H)-yl)benzoic a...)
Affinity DataIC50: 3.30E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324471((E)-4-(4-oxo-2-styrylquinazolin-3(4H)-yl)benzoic a...)
Affinity DataIC50: 8.40E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324471((E)-4-(4-oxo-2-styrylquinazolin-3(4H)-yl)benzoic a...)
Affinity DataIC50: 8.50E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed