BDBM50324627 6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol::CHEMBL1214739

SMILES Oc1ccc2cc(ccc2c1)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=OCQPVXWUPNNJIV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324627   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50: 438nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50: 627nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324627(6-[4-(Pyridin-4-ylmethyl)phenyl]naphthalen-2-ol | ...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed