BDBM50328475 CHEMBL1259187::N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-1-yl)ethyl)piperidin-4-yl)-1H-indol-5-yl)methyl)acetamide

SMILES CC(=O)NCc1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1

InChI Key InChIKey=KEEXCUUQRQNRNF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328475   

TargetAlpha-1A adrenergic receptor(Bovine)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]prozosin from bovine cloned Alpha-1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]prozosin from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328475(N-((1-(4-fluorophenyl)-3-(1-(2-(2-oxoimidazolidin-...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]prozosin from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed