BDBM50331854 CHEMBL1241832::N'-((2-hydroxynaphthalen-1-yl)methylene)-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide::N'-[(2-hydroxy-1-naphthyl)methylene]-3-(2-naphthyl)-1H-pyrazole-5-carbohydrazide

SMILES Oc1ccc2ccccc2c1C=NNC(=O)c1cc(n[nH]1)-c1ccc2ccccc2c1

InChI Key InChIKey=XOXCTLAKMCIWCF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331854   

TargetSphingosine kinase 1(Human)
Pennsylvania State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50331854(N'-((2-hydroxynaphthalen-1-yl)methylene)-3-(naphth...)
Affinity DataKi:  1.06E+3nMAssay Description:Competitive inhibition of recombinant sphingosine kinase 1 using D-erythro-sphingosine as substrate by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Pennsylvania State University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50331854(N'-((2-hydroxynaphthalen-1-yl)methylene)-3-(naphth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length GST-tagged human SPHK1 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Alex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed