BDBM50332046 CHEMBL1288186::methyl 3-(2-(4-(trifluoromethyl)phenyl)acetamido)thiophene-2-carboxylate

SMILES COC(=O)c1sccc1NC(=O)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ABOQVROUVXWAOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332046   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332046(methyl 3-(2-(4-(trifluoromethyl)phenyl)acetamido)t...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332046(methyl 3-(2-(4-(trifluoromethyl)phenyl)acetamido)t...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332046(methyl 3-(2-(4-(trifluoromethyl)phenyl)acetamido)t...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed