BDBM50332328 2-(3,4-difluorobenzyl)-3-(isopropylamino)-1-(4-((S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl)piperazin-1-yl)propan-1-one::CHEMBL1632383

SMILES CC(C)NCC(Cc1ccc(F)c(F)c1)C(=O)N1CCN(CC1)c1ncnc2CS[C@@H](C)c12

InChI Key InChIKey=FJSOOWAXPRYKKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332328   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50332328(2-(3,4-difluorobenzyl)-3-(isopropylamino)-1-(4-((S...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50332328(2-(3,4-difluorobenzyl)-3-(isopropylamino)-1-(4-((S...)
Affinity DataIC50: 759nMAssay Description:Inhibition of Akt in human LNCaP cell assessed as inhibition of PRAS40 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed