BDBM50335456 1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl)azetidine-3-carboxylic acid::CHEMBL1651710

SMILES CCCCOc1ccc2oc(cc2c1)-c1ncc(CN2CC(C2)C(O)=O)s1

InChI Key InChIKey=LHCOLDKKHIYDRM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335456   

TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335456(1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl...)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335456(1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human S1P1R expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335456(1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed