BDBM50337615 CHEMBL1683070::cis-((1S,3R)-3-(3-ethoxy-tetrahydro-2H-pyran-4-ylamino)-1-isopropylcyclopentyl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone

SMILES CCO[C@H]1COCC[C@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=PEFVTWREQBVUOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337615   

TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337615(cis-((1S,3R)-3-(3-ethoxy-tetrahydro-2H-pyran-4-yla...)
Affinity DataIC50: 66nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337615(cis-((1S,3R)-3-(3-ethoxy-tetrahydro-2H-pyran-4-yla...)
Affinity DataIC50: 206nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed