BDBM50338435 (R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidin-5-yl)piperidin-4-yl)ethanamine::CHEMBL1683141

SMILES COc1ncc(cn1)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F

InChI Key InChIKey=FLORMQPGMJTURD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338435   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338435((R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidi...)
Affinity DataIC50: 78nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338435((R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidi...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338435((R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidi...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338435((R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidi...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338435((R)-2-(2,5-difluorophenyl)-1-(1-(2-methoxypyrimidi...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed