BDBM50339768 2-(4-chloro-2-(((3S,5R)-3,5-dimethyl-4-(2-phenylacetyl)piperazin-1-yl)methyl)phenoxy)acetic acid::CHEMBL1689125

SMILES C[C@H]1CN(Cc2cc(Cl)ccc2OCC(O)=O)C[C@@H](C)N1C(=O)Cc1ccccc1

InChI Key InChIKey=AFHZNYOZSHABDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339768   

TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339768(2-(4-chloro-2-(((3S,5R)-3,5-dimethyl-4-(2-phenylac...)
Affinity DataIC50: 71nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339768(2-(4-chloro-2-(((3S,5R)-3,5-dimethyl-4-(2-phenylac...)
Affinity DataIC50: 3.84E+3nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed