BDBM50352402 CHEMBL1823847

SMILES COc1cc2ccccc2nc1-c1noc(n1)C1CCN(CC1)C(=O)Nc1ccccc1Cl

InChI Key InChIKey=AGQWQTRMTRWJCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352402   

TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352402(CHEMBL1823847)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352402(CHEMBL1823847)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed