BDBM50354822 CHEMBL302453

SMILES Nc1ccncn1

InChI Key InChIKey=OYRRZWATULMEPF-UHFFFAOYSA-N

Data  4 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50354822   

TargetHeat shock protein HSP 90-alpha(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354822(CHEMBL302453)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to human HSP90alpha assessed as 2D1H-15N chemical shift perturbation by NMR spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
TBA

Curated by ChEMBL
LigandPNGBDBM50354822(CHEMBL302453)
Affinity DataKi:  4.20E+6nMpH: 8.25Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
TBA

Curated by ChEMBL
LigandPNGBDBM50354822(CHEMBL302453)
Affinity DataKi:  5.00E+6nMpH: 7.0Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
TBA

Curated by ChEMBL
LigandPNGBDBM50354822(CHEMBL302453)
Affinity DataKi:  8.90E+6nMpH: 7.0Assay Description:Noncompetitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 7 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
TBA

Curated by ChEMBL
LigandPNGBDBM50354822(CHEMBL302453)
Affinity DataKi:  9.70E+6nMpH: 8.25Assay Description:Competitive inhibition of electric eel AChE using acetylthiocholine chloride as substrate at pH 8.25 by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed