BDBM50357623 CHEMBL1915671

SMILES CN1C[C@@H](COc2cc(C)c(cc2C)C(=O)Nc2cccc(CC(O)=O)c2)Oc2ccccc12

InChI Key InChIKey=KDQQDGQGYXWECN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357623   

TargetProstaglandin D2 receptor(Mouse)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357623(CHEMBL1915671)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357623(CHEMBL1915671)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed