BDBM50361052 CHEMBL1935589::CHEMBL1949758

SMILES O=S(=O)(c1ccccc1)c1ccc2c3CCNCc3oc2c1

InChI Key InChIKey=HKCRMSMUMPAIPI-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50361052   

Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361052(CHEMBL1949758 | CHEMBL1935589)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361052(CHEMBL1949758 | CHEMBL1935589)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361052(CHEMBL1949758 | CHEMBL1935589)
Affinity DataIC50: 8.5nMAssay Description:Antagonist activity at human recombinant 5-HT6 receptor expressed human astrocytoma cells assessed as inhibition of 5-HT-induced cAMP accumulation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361052(CHEMBL1949758 | CHEMBL1935589)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed