BDBM50362709 CHEMBL1939782

SMILES Cc1cc(cc2c1nc3c(c2N4CCNCC4)c(n[nH]3)C)OC

InChI Key InChIKey=LRBQTFPUUPFJQW-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362709   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataIC50: 320nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataIC50: 858nMAssay Description:Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362709(CHEMBL1939782)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant human PDE5A using [3H]cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed