BDBM50385626 CHEMBL2042378

SMILES CN1C(=O)N(Cc2csc(n2)-c2ccccc2)C(=O)C11C(=O)N(CC(O)=O)c2ccc(Cl)cc12

InChI Key InChIKey=ASSMTOZUONKVFM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50385626   

TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385626(CHEMBL2042378)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in CHO cells after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50385626(CHEMBL2042378)
Affinity DataIC50: 3.94E+3nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change pretreated for 20 mins meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed