BDBM50393034 CHEMBL2152704

SMILES Cc1ccc(cc1N2c3c(c(ncn3)N)C4=C(C2=O)CCCC4)O

InChI Key InChIKey=ZQQZSFIPDUAFMC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50393034   

TargetEphrin type-B receptor 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 160nMAssay Description:Inhibition of EphB4 in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 300nMAssay Description:Inhibition of EphB4 by FRET assay in presence of 30 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 338nMAssay Description:Inhibition of recombinant Src catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 864nMAssay Description:Inhibition of recombinant Abl1 catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 930nMAssay Description:Inhibition of human full length EphB4 expressed in MEF cells assessed as inhibition of human ephrin B2/FC chimera-stimulated receptor autophosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant Lck catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393034(CHEMBL2152704)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant EGFR catalytic domain in presence of 1 uM radiolabeled ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed