BDBM50403482 CHEMBL5267044

SMILES Cc1c(ccc2c1[nH]cc2/C=C\3/C(=O)N(C(=O)N3)Cc4ccc(c(c4)F)F)Cl

InChI Key InChIKey=OEXMEVPQEPHTAQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50403482   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 30nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 33nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 33nMAssay Description:Inhibition of human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 41nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 41nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)