BDBM50416872 CHEMBL1257342

SMILES CC(C)(CC(O)(CNc1cccc2ccccc12)C(F)(F)F)c1cc(F)ccc1O

InChI Key InChIKey=LCQARUZGGLOLJC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416872   

TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416872(CHEMBL1257342)
Affinity DataIC50: 15.8nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416872(CHEMBL1257342)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant androgen receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416872(CHEMBL1257342)
Affinity DataIC50: 1.00E+3nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL-8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416872(CHEMBL1257342)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant progesterone receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416872(CHEMBL1257342)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human recombinant mineralocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed