BDBM50418048 CHEMBL1688408::US10851083, Example 129::US11618744, Example 129

SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(F)cc2[nH]1)C(F)(F)F

InChI Key InChIKey=OTYMTMJAFGWNSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418048   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50418048(CHEMBL1688408 | US10851083, Example 129 | US116187...)
Affinity DataIC50: 100nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50418048(CHEMBL1688408 | US10851083, Example 129 | US116187...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PHD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50418048(CHEMBL1688408 | US10851083, Example 129 | US116187...)
Affinity DataIC50: 100nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent