BDBM50429736 CHEMBL1164630

SMILES Oc1ccc(\C=C\C(=O)Nc2cccc(Cl)c2)cc1O

InChI Key InChIKey=HQSAGGSYGVYRMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429736   

Target72 kDa type IV collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429736(CHEMBL1164630)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429736(CHEMBL1164630)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50429736(CHEMBL1164630)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed