BDBM50434997 CHEMBL2386074

SMILES OC(=O)Cn1c2CCN(Cc2c2ccccc12)C(=O)C1CCCCC1

InChI Key InChIKey=MWALGAXFBJFLOX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434997   

TargetProstaglandin D2 receptor 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434997(CHEMBL2386074)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in HEK293 cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434997(CHEMBL2386074)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293 cells assessed as inhibition of PGD2-induced calcium flux after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434997(CHEMBL2386074)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human prostanoid TP2 receptor expressed in HEK293 cells assessed as inhibition of calcium flux after 30 to 40 mins by FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed