BDBM50436048 CHEMBL2396745

SMILES CC(C)(C)NC(=O)C(c1c2ccc(cc2[nH]c1C(=O)O)Cl)N(Cc3ccc(c(c3)F)F)C=O

InChI Key InChIKey=AGRQHAQMUFKJFC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436048   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50436048(CHEMBL2396745)
Affinity DataKi:  250nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed