BDBM50439272 CHEMBL2419495

SMILES CCOC(=O)c1cc(C#N)c(nc1C)N1CCC(CC1)C(=O)NS(=O)(=O)Cc1ccc(F)cc1F

InChI Key InChIKey=AHQASDPCJPXGHL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439272   

TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50439272(CHEMBL2419495)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) expressed in CHO cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50439272(CHEMBL2419495)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50439272(CHEMBL2419495)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at P2Y12 receptor in human whole blood assessed as inhibition of ADP-induced platelet aggregation after 5 mins by residual platel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50439272(CHEMBL2419495)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed