BDBM50449310 CHEMBL3125387

SMILES CC1CN(C(=O)Cc2nc(sc2C(N)=O)N2CCOCC2)c2ccccc12

InChI Key InChIKey=VRFSADMGIMNNAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50449310   

LigandPNGBDBM50449310(CHEMBL3125387)
Affinity DataIC50: 75nMAssay Description:Inhibition of PI3Kbeta in human PTEN-deficient PC3 cells assessed as Akt phosphorylation at S473More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandPNGBDBM50449310(CHEMBL3125387)
Affinity DataIC50: 130nMAssay Description:Inhibition of human PI3Kbeta after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandPNGBDBM50449310(CHEMBL3125387)
Affinity DataIC50: 567nMAssay Description:Inhibition of human PI3Kdelta after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandPNGBDBM50449310(CHEMBL3125387)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human PI3Kgamma after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
LigandPNGBDBM50449310(CHEMBL3125387)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed