BDBM50449311 CHEMBL3125384
SMILES CC1Cc2c(cccc2Br)N1C(=O)Cc1nc(sc1C(O)=O)N1CCOCC1
InChI Key InChIKey=KAKATSTZIXKFNX-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50449311
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human PI3Kbeta after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human PI3Kbeta after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of PI3Kbeta in human PTEN-deficient PC3 cells assessed as Akt phosphorylation at S473More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of PI3Kbeta in human PTEN-deficient PC3 cells assessed as Akt phosphorylation at S473More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 861nMAssay Description:Inhibition of human PI3Kdelta after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 861nMAssay Description:Inhibition of human PI3Kdelta after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of human PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kgamma after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kgamma after 15 minsMore data for this Ligand-Target Pair