BDBM50457614 CHEMBL4202524

SMILES CN1CNS(=O)(=O)c2c1cc(cc2)CCc3ccc4c(c3)N(CNS4(=O)=O)C

InChI Key InChIKey=PZUOXMWBXQXKJK-UHFFFAOYSA-N

Data  2 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457614   

TargetGlutamate receptor 2(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50457614(CHEMBL4202524)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50457614(CHEMBL4202524)
Affinity DataEC50:  14.5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed