BDBM50478469 7,12-O,O''dibenzyl-N-methylcoclaurine::CHEMBL452763

SMILES COc1cc2CCN(C)C(Cc3ccc(OCc4ccccc4)cc3)c2cc1OCc1ccccc1

InChI Key InChIKey=HZBGXMAYXSMTBE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50478469   

TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50478469(7,12-O,O''dibenzyl-N-methylcoclaurine | CHEMBL4527...)
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50478469(7,12-O,O''dibenzyl-N-methylcoclaurine | CHEMBL4527...)
Affinity DataKi:  7.59E+3nMAssay Description:Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed