BDBM50526481 CHEMBL4524183

SMILES c1ccc2c(c1)cc(cn2)C#N

InChI Key InChIKey=QZZYYBQGTSGDPP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526481   

TargetHematopoietic prostaglandin D synthase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50526481(CHEMBL4524183)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) using PGH2 as substrate measured after 90 to 120 secs by R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50526481(CHEMBL4524183)
Affinity DataIC50: 2.20E+5nMAssay Description:Binding affinity to full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by Green fluorescent probe-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed