BDBM50778 (1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-thienyl)-3,8a-dihydro-2H-indolizine-1-carboxylic acid ethyl ester::(1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-thiophenyl)-3,8a-dihydro-2H-indolizine-1-carboxylic acid ethyl ester::MLS000028120::SMR000038911::cid_658017::ethyl (1S,2S,3R,8aS)-3-aminocarbonyl-1-cyano-6-ethanoyl-2-thiophen-3-yl-3,8a-dihydro-2H-indolizine-1-carboxylate::ethyl (1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-thiophen-3-yl-3,8a-dihydro-2H-indolizine-1-carboxylate

SMILES CCOC(=O)[C@]1(C#N)[C@@H]2C=CC(=CN2[C@H]([C@@H]1c1ccsc1)C(N)=O)C(C)=O

InChI Key InChIKey=WJXIZLBMJFLASA-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50778   

TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataEC50:  2.50E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataIC50: 3.83E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataEC50:  1.23E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay