BDBM59670 6-amino-3-(4-fluorophenyl)-4-(4-pyridyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-3-(4-fluorophenyl)-4-pyridin-4-yl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-3-(4-fluorophenyl)-4-pyridin-4-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-azanyl-3-(4-fluorophenyl)-4-pyridin-4-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::MLS000043828::SMR000021039::cid_3240800

SMILES Fc1ccc(cc1)-c1n[nH]c2OC(=N)C(C#N)C(c12)c1ccncc1

InChI Key InChIKey=WWTUZFBBLUCEOJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59670   

TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM59670(6-amino-3-(4-fluorophenyl)-4-pyridin-4-yl-2,4-dihy...)
Affinity DataEC50:  5.79E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM59670(6-amino-3-(4-fluorophenyl)-4-pyridin-4-yl-2,4-dihy...)
Affinity DataEC50:  4.32E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM59670(6-amino-3-(4-fluorophenyl)-4-pyridin-4-yl-2,4-dihy...)
Affinity DataIC50: 9.43E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay