BDBM65913 2-[1-(2-chlorobenzyl)indol-3-yl]sulfonyl-N-(5-methylisoxazol-3-yl)acetamide::2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N-(5-methyl-1,2-oxazol-3-yl)acetamide::2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N-(5-methyl-1,2-oxazol-3-yl)ethanamide::2-[[1-[(2-chlorophenyl)methyl]-3-indolyl]sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide::VU0108370-10::cid_2157678

SMILES Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3ccccc3Cl)c3ccccc23)no1

InChI Key InChIKey=FPBRFRSODHILCO-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65913   

TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50:  9.71E+3nMAssay Description:Allosteric modulation at rat M1 receptor expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50:  1.00E+4nMAssay Description:Assay Provider: P. Jeffery Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 Mus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt Institute of Chemical Biology/Chemical Synthesis Core

Curated by ChEMBL
LigandPNGBDBM65913(2-[1-[(2-chlorophenyl)methyl]indol-3-yl]sulfonyl-N...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed