BDBM66626 2-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)ethyl acetate::2-[7,8-dimethyl-2,4-bis(oxidanylidene)benzo[g]pteridin-10-yl]ethyl ethanoate::Isoalloxazine, 10-(2-hydroxyethyl)-7,8-dimethyl-, acetate::MLS000736493::SMR000528043::acetic acid 2-(2,4-diketo-7,8-dimethyl-benzo[g]pteridin-10-yl)ethyl ester::acetic acid 2-(7,8-dimethyl-2,4-dioxo-10-benzo[g]pteridinyl)ethyl ester::cid_22641

SMILES CC(=O)OCCn1c2cc(C)c(C)cc2nc2c1nc(=O)[nH]c2=O

InChI Key InChIKey=PVRDHKBVCDWVPD-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66626   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM66626(cid_22641 | 2-[7,8-dimethyl-2,4-bis(oxidanylidene)...)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetMitochondrial peptide methionine sulfoxide reductase(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66626(cid_22641 | 2-[7,8-dimethyl-2,4-bis(oxidanylidene)...)
Affinity DataEC50:  5.44E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetProtein LANA1(HHV-8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66626(cid_22641 | 2-[7,8-dimethyl-2,4-bis(oxidanylidene)...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66626(cid_22641 | 2-[7,8-dimethyl-2,4-bis(oxidanylidene)...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay