BDBM69641 1,3-Diphenyl-1H-pyrazole-4-carbaldehyde::1,3-diphenyl-4-pyrazolecarboxaldehyde::1,3-diphenylpyrazole-4-carbaldehyde::MLS001211287::SMR000517359::cid_555820

SMILES O=Cc1cn(nc1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=LZGBMIZREYTWRI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 69641   

TargetProstaglandin G/H synthase 2(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM69641(SMR000517359 | 1,3-Diphenyl-1H-pyrazole-4-carbalde...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate incubated for 30 secs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMitochondrial peptide methionine sulfoxide reductase(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM69641(SMR000517359 | 1,3-Diphenyl-1H-pyrazole-4-carbalde...)
Affinity DataIC50: 1.55E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69641(SMR000517359 | 1,3-Diphenyl-1H-pyrazole-4-carbalde...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay